Dr. McCullough was born in Shreveport, Louisiana and completed his undergraduate education at Louisiana State University. He then attended Mount Sinai School of Medicine, where he graduated in 2012 with Distinction in Medical Education and received the Harold Elster Memorial Prize for Highest Academic Standing. Following medical school, he completed Internal Medicine residency at the Massachusetts General Hospital and Harvard Medical School in Boston. He then completed his training in cardiovascular diseases and echocardiography at Mount Sinai Hospital, where he served as Chief Cardiology Fellow.

Dr. McCullough's main clinical interests include studying methods to improve the cardiovascular education of trainees, how diagnostic testing can be best utilized to make appropriate therapeutic recommendations for patients, and the role of diagnostic testing in identifying our patients at highest risk.