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Scholars @ Weill Cornell Medicine

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Scholars8,803 Publications201,348 Funding7,268 Clinical research176

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Browse

Scholars8,803 Publications201,348 Funding7,268 Clinical research176

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Status

Recruiting53
Not yet recruiting3
Enrolling by invitation2
Active, not recruiting54
Completed51
Terminated13

Study type

Interventional176
Observational26

Phase

Not applicable71
Phase 353
Phase 239
Phase 14
Phase 44
Phase 1/23

Investigator

Hani Lamie Ashamalla7
Dana Jeremy Lukin6
Alexander Ja-Ho Chou5
Evelyn Cantillo4
Manish A Shah4

Department

Medicine88
Obstetrics and Gynecology16
Pediatrics13
Neurology9
Radiation Oncology9

Condition

Prostatic Neoplasms8
Colitis, Ulcerative7
Heart Failure7
Breast Neoplasms6
Crohn Disease6

Intervention type

Other176
Drug788
Device166
Biological150
Procedure119
Behavioral83

Sponsor type

Industry53
WCM (investigator-initiated)48
Other academic42
NIH21
Cooperative group12

Start date

Has results posted38

Interventional×Other×Clear all

Showing 1–20 of 176 studiesSort:

Active, not recruitingInterventional · Phase 3NCT02193282 ↗
Randomized Study of Erlotinib Vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

FiltersClear all

Status

Recruiting53
Not yet recruiting3
Enrolling by invitation2
Active, not recruiting54
Completed51
Terminated13

Study type

Interventional176
Observational26

Phase

Not applicable71
Phase 353
Phase 239
Phase 14
Phase 44
Phase 1/23

Investigator

Hani Lamie Ashamalla7
Dana Jeremy Lukin6
Alexander Ja-Ho Chou5
Evelyn Cantillo4
Manish A Shah4

Department

Medicine88
Obstetrics and Gynecology16
Pediatrics13
Neurology9
Radiation Oncology9

Condition

Prostatic Neoplasms8
Colitis, Ulcerative7
Heart Failure7
Breast Neoplasms6
Crohn Disease6

Intervention type

Other176
Drug788
Device166
Biological150
Procedure119
Behavioral83

Sponsor type

Industry53
WCM (investigator-initiated)48
Other academic42
NIH21
Cooperative group12

Start date

Has results posted38

Interventional×Other×Clear all

Showing 1–20 of 176 studiesSort:

Active, not recruitingInterventional · Phase 3NCT02193282 ↗
Randomized Study of Erlotinib Vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

Phase 2/3

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Scott T. Tagawa4
Ana M. Molina3
Catherine Butkus Small3
Cora Sternberg3
Daniel W Skupski3
Eleni Andreopoulou3
Grant Ellsworth3
Jia Ruan3
Louis J Aronne3
Ashish Saxena2
Anais Rameau2
Bernhard Kuhn2
Cheguevara Afaneh2
Erica Phillips2
Georgiana Alina Dobri2
Howard Alan Fine2
Harini Sarva2
Holly G Prigerson2
Heather Lipkind2
Jeremy Adam Weingarten2
Mehraneh Dorna Jafari2
Melissa Frey2
Neel Mehta2
Parag Goyal2
Randy Longman2
Shari Lipner2
Shoshana Rosenberg2
Sonal Kumar2
Veerawat Phongtankuel2
Tony Rosen1
Allyson J Ocean1
Anna Podolanczuk1
Alexander Drelick1
Andrew F. Alexis1
Aliza B Solomon1
Aileen Gariepy1
Anthony O. Ahmed1
Alpana P. Shukla1
Bassem M Masri1
Brock Daniels1
Bradley B Pua1
Christine M Salvatore1
Carrie Johnston1
Conor Liston1
Carl V. Crawford1

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Emergency Medicine5
Neurological Surgery5
Surgery5
Anesthesiology4
Psychiatry4
Dermatology3
Otolaryngology Head and Neck Surgery3
Population Health Sciences3
Radiology3
Rehabilitation Medicine2
Urology2
Cardiothoracic Surgery1
Orthopaedic Surgery1
Pharmacology1

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Obesity6
Carcinoma, Non-Small-Cell Lung4
Hypertension4
Inflammatory Bowel Diseases4
Overweight4
Anxiety Disorders3
Breast Carcinoma In Situ3
COVID-193
Carcinoma, Renal Cell3
Diabetes Mellitus, Type 23
Hodgkin Disease3
Lung Neoplasms3
Neoplasms3
Nutrition Disorders3
Pain3
Papillomavirus Infections3
Parkinson Disease3
Acquired Immunodeficiency Syndrome2
Acute Coronary Syndrome2
Atrial Fibrillation2
Brain Neoplasms2
Burkitt Lymphoma2
Carcinosarcoma2
Caregiver Burden2
Chronic Pain2
Coronavirus Infections2
Depression2
Depression, Postpartum2
Endocrine System Diseases2
Glioblastoma2
Leukemia, Biphenotypic, Acute2
Leukemia, Myeloid, Acute2
Metabolic Diseases2
Pancreatic Neoplasms2
Patient Participation2
Respiratory Distress Syndrome2
Triple Negative Breast Neoplasms2
Urinary Bladder Neoplasms2
ACTH Syndrome, Ectopic1
Adenocarcinoma Of Esophagus1
Adenocarcinoma of Lung1
Aggression1
Agnosia1
Alveolitis, Extrinsic Allergic1
Alzheimer Disease1

Radiation61

Diagnostic test22

Dietary supplement14

Combination product11

Genetic6

Ashish SaxenaPI

Intervention: Other: Clinical Observation · Drug: Erlotinib Hydrochloride · Other: Laboratory Biomarker Analysis · Other: Placebo Administration
Dates: Feb 2015 – Dec 2025
Sponsor: Alliance for Clinical Trials in Oncology

Lung Non-Squamous Non-Small Cell CarcinomaStage IB Lung Non-Small Cell Carcinoma AJCC v7Stage II Lung Non-Small Cell Cancer AJCC v7+3 more

Active, not recruitingInterventional · Phase 3NCT02954874 ↗

A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With >/= 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN1mi, ypN1-3) After Neoadjuvant Chemotherapy

Eleni AndreopoulouPI

Intervention: Procedure: Biospecimen Collection · Other: Laboratory Biomarker Analysis · Other: Patient Observation · Biological: Pembrolizumab · Other: Quality-of-Life Assessment · Other: Questionnaire Administration · Radiation: Radiation Therapy
Dates: Jan 2017 – Aug 2026
Sponsor: Southwest Oncology Group

Breast Carcinoma In SituInvasive Breast CarcinomaStage I Breast Cancer AJCC v7+3 more

Active, not recruitingInterventional · Phase 2NCT03092856 ↗

Phase II Randomized Double Blind Trial of PF-04518600, an OX40 Antibody, in Combination With Axitinib Versus Axitinib in Immune-Checkpoint Inhibitor Exposed Patients With Metastatic Renal Cell Carcinoma

Ana M. MolinaPI

Intervention: Biological: Anti-OX40 Antibody PF-04518600 · Drug: Axitinib · Other: Laboratory Biomarker Analysis · Other: Placebo
Dates: Jul 2017 – Dec 2026 (est.)
Sponsor: USC Keck School of Medicine Norris Cancer Center

Clear Cell Renal Cell CarcinomaMetastatic Renal Cell CancerRecurrent Renal Cell Carcinoma+1 more

Active, not recruitingInterventional · Phase 4NCT03315910 ↗

Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

Bradley B PuaPI

Intervention: Behavioral: Motivational Interviewing (MI) · Drug: Nicotine Replacement Therapy (NRT) · Drug: Nicotine Lozenge · Behavioral: Message Framing · Other: saliva sample
Dates: Oct 2017 – Oct 2027 (est.)
Sponsor: Memorial Sloan Kettering Cancer Center

Smoking Cessation

Active, not recruitingInterventional · Phase 2NCT03371719 ↗

A Phase II, Double-Blinded, Placebo-Controlled Randomized Trial of Salvage Radiotherapy With or Without Enhanced Anti-Androgen Therapy With Apalutamide in Recurrent Prostate Cancer (BALANCE*)

Hani Lamie AshamallaPI

Intervention: Drug: Apalutamide · Radiation: External Beam Radiation Therapy · Other: Placebo Administration
Dates: Jun 2018 – Mar 2025· Results posted
Sponsor: NRG Oncology

Recurrent Prostate CarcinomaStage III Prostate Adenocarcinoma AJCC v7Stage IV Prostate Adenocarcinoma AJCC v7

Active, not recruitingInterventional · Not applicableNCT03487185 ↗

A Randomized Trial of Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

Daniel W SkupskiPI

Intervention: Device: Continuous Positive Airway Pressure · Other: Sleep Advice Control
Dates: Aug 2018 – Oct 2026 (est.)
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Develop

Obstructive Sleep Apnea of AdultPreeclampsiaObstetrical Complications

Active, not recruitingInterventional · Phase 3NCT03488693 ↗

TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

Hani Lamie AshamallaPI

Intervention: Radiation: Radiation · Other: No Radiation
Dates: Oct 2018 – Sep 2027 (est.)
Sponsor: Canadian Cancer Trials Group

Breast Cancer

Active, not recruitingInterventional · Not applicableNCT03499236 ↗

RELIEVE-HF TRIAL: REducing Lung congestIon Symptoms Using the v-wavE Shunt in adVancEd Heart Failure

Maria KarasPI

Intervention: Device: V-Wave Interatrial Shunt · Other: Control
Dates: Sep 2018 – Oct 2023
Sponsor: V-Wave Ltd.

Heart Failure

Active, not recruitingInterventional · Phase 3NCT03533582 ↗

Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

Alexander Ja-Ho ChouPI

Intervention: Procedure: Biospecimen Collection · Drug: Carboplatin · Drug: Cisplatin · Drug: Doxorubicin · Drug: Etoposide · Drug: Fluorouracil · Drug: Gemcitabine · Drug: Irinotecan · Drug: Oxaliplatin · Other: Patient Observation · Procedure: Resection · Drug: Sorafenib · Drug: Vincristine Sulfate
Dates: May 2018 – Mar 2027 (est.)
Sponsor: Children's Oncology Group

Childhood Hepatocellular CarcinomaChildhood Malignant Liver NeoplasmFibrolamellar Carcinoma+2 more

RecruitingInterventional · Phase 3NCT03678025 ↗

Phase III Randomized Trial of Standard Systemic Therapy (SST) Versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer

Douglas S ScherrPI

Intervention: Drug: Abiraterone · Drug: Bicalutamide · Drug: Degarelix · Drug: Docetaxel · Drug: Flutamide · Drug: Goserelin Acetate · Drug: Histrelin Acetate · Drug: Leuprolide Acetate · Drug: Nilutamide · Procedure: Orchiectomy · Drug: Prednisone · Other: Quality-of-Life Assessment · Radiation: Radiation Therapy · Procedure: Radical Prostatectomy · Drug: Triptorelin
Dates: Sep 2018 – Apr 2033 (est.)
Sponsor: Southwest Oncology Group

Castration Levels of TestosteroneMetastatic Prostatic AdenocarcinomaStage IV Prostate Cancer AJCC v8+2 more

Active, not recruitingInterventional · Phase 2NCT03712202 ↗

A Phase 2 Front-Line PET/CT-2 Response-Adapted Brentuximab Vedotin and Nivolumab Incorporated and Radiation-Free Management of Early Stage Classical Hodgkin Lymphoma (cHL)

Jia RuanPI

Intervention: Drug: Bleomycin · Drug: Brentuximab Vedotin · Drug: Dacarbazine · Drug: Doxorubicin · Biological: Nivolumab · Other: Quality-of-Life Assessment · Drug: Vinblastine
Dates: Nov 2018 – Nov 2024· Results posted
Sponsor: City of Hope National Medical Center

Ann Arbor Stage I Hodgkin LymphomaAnn Arbor Stage I Mixed Cellularity Classic Hodgkin LymphomaAnn Arbor Stage I Nodular Sclerosis Classic Hodgkin Lymphoma+11 more

Active, not recruitingInterventional · Phase 3NCT03737981 ↗

A Randomized Phase III Study of Ibrutinib Plus Obinutuzumab Versus Ibrutinib Plus Venetoclax and Obinutuzumab in Untreated Older Patients (>/= 65 Years of Age) With Chronic Lymphocytic Leukemia (CLL)

John AllanPI

Intervention: Drug: Ibrutinib · Biological: Obinutuzumab · Other: Observation Activity · Drug: Venetoclax
Dates: Jan 2019 – Jan 2025· Results posted
Sponsor: Alliance for Clinical Trials in Oncology

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

Active, not recruitingInterventional · Not applicableNCT03754114 ↗

Brain Oxygen Optimization in Severe TBI (BOOST3): A Comparative Effectiveness Study to Test the Efficacy of a Prescribed Treatment Protocol Based on Monitoring the Partial Pressure of Brain Tissue Oxygen.

Margaret HuynhPI

Intervention: Other: ICP + PbtO2 guided management strategy · Other: ICP guided management strategy
Dates: Aug 2019 – Nov 2027 (est.)
Sponsor: National Institute of Neurological Disorders & Stroke

Brain Injuries, Traumatic

Active, not recruitingInterventional · Phase 3NCT03793166 ↗

PD-Inhibitor (Nivolumab) and Ipilimumab Followed by Nivolumab Vs. VEGF TKI Cabozantinib With Nivolumab: A Phase III Trial in Metastatic Untreated REnal Cell CancEr [PDIGREE]

Ana M. MolinaPI

Intervention: Procedure: Biospecimen Collection · Procedure: Bone Scan · Drug: Cabozantinib · Procedure: Computed Tomography · Biological: Ipilimumab · Procedure: Magnetic Resonance Imaging · Biological: Nivolumab · Other: Quality-of-Life Assessment · Other: Questionnaire Administration
Dates: Jun 2019 – Mar 2028 (est.)
Sponsor: Alliance for Clinical Trials in Oncology

Clear Cell Renal Cell CarcinomaMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the Lymph Nodes+6 more

Active, not recruitingInterventional · Phase 3NCT03803553 ↗

Early Identification and Treatment of Occult Metastatic Disease in Stage III Colon Cancer

Manish A ShahPI

Intervention: Drug: FOLFIRI Protocol · Other: ACTIVE SURVEILLANCE · Drug: Nivolumab Protocol · Drug: Encorafenib/Binimetinib/Cetuximab Protocol · Drug: Trastuzumab + Pertuzumab
Dates: Apr 2020 – Dec 2026 (est.)
Sponsor: The General Hospital Corporation (dba Massachusetts General Hospital)

Metastatic Colon CancerStage III Colon Cancer

Active, not recruitingInterventional · Phase 3NCT03811015 ↗

A Phase III Randomized Study of Maintenance Nivolumab Versus Observation in Patients With Locally Advanced, Intermediate Risk HPV Positive OPSCC

Hani Lamie AshamallaPI

Intervention: Procedure: Biospecimen Collection · Drug: Cisplatin · Procedure: Computed Tomography · Procedure: Echocardiography Test · Other: Fludeoxyglucose F-18 · Radiation: Intensity-Modulated Radiation Therapy · Biological: Nivolumab · Other: Patient Observation · Procedure: Positron Emission Tomography
Dates: Aug 2019 – Jan 2030 (est.)
Sponsor: ECOG-ACRIN Cancer Research Group

Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Active, not recruitingInterventional · Phase 2NCT03817398 ↗

Stopping Tyrosine Kinase Inhibitors (TKI) to Assess Treatment-Free Remission (TFR) in Pediatric Chronic Myeloid Leukemia - Chronic Phase (CML-CP)

Alexander Ja-Ho ChouPI

Intervention: Procedure: Biospecimen Collection · Other: Drug Withdrawn · Other: Quality-of-Life Assessment · Other: Questionnaire Administration · Drug: Tyrosine Kinase Inhibitor
Dates: Nov 2019 – Sep 2026 (est.)
Sponsor: Children's Oncology Group

Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

Active, not recruitingInterventional · Phase 3NCT03833154 ↗

A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab With Stereotactic Body Radiation Therapy (SBRT) for the Treatment of Patients With Unresected Stage I/II, Lymph-node Negative Non-small Cell Lung Cancer (PACIFIC-4/RTOG-3515) Osimertinib Following SBRT, a Single Arm Cohort for Patients With Unresected Stage I/II, Lymph Node Negative NSCLC Harboring a Sensitizing EGFR Mutation

Silvia Chiara FormentiPI

Intervention: Drug: Durvalumab · Other: Placebo · Drug: (Osimertinib cohort, single-arm, open-label separate cohort)
Dates: Mar 2019 – Oct 2028 (est.)
Sponsor: AstraZeneca, PLC

Carcinoma, Non-Small-Cell Lung

Active, not recruitingInterventional · Phase 3NCT03907488 ↗

A Phase III, Randomized Study of Nivolumab (Opdivo) Plus AVD or Brentuximab Vedotin (Adcetris) Plus AVD in Patients (Age >/= 12 Years) With Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma

Jia RuanPI

Intervention: Procedure: Biospecimen Collection · Drug: Brentuximab Vedotin · Procedure: Computed Tomography · Drug: Dacarbazine · Drug: Doxorubicin Hydrochloride · Biological: Filgrastim · Procedure: Magnetic Resonance Imaging · Biological: Nivolumab · Biological: Pegfilgrastim · Procedure: Positron Emission Tomography · Other: Quality-of-Life Assessment · Other: Questionnaire Administration · Radiation: Radiation Therapy · Drug: Vinblastine Sulfate
Dates: Aug 2019 – Mar 2024· Results posted
Sponsor: Southwest Oncology Group

Ann Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Lymphocyte-Depleted Classic Hodgkin LymphomaAnn Arbor Stage III Mixed Cellularity Classic Hodgkin Lymphoma+7 more

Active, not recruitingInterventional · Phase 3NCT03914612 ↗

A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864) in Addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer

Evelyn CantilloPI

Intervention: Drug: Carboplatin · Procedure: Computed Tomography · Drug: Paclitaxel · Biological: Pembrolizumab · Other: Placebo Administration · Other: Quality-of-Life Assessment · Other: Questionnaire Administration
Dates: Aug 2019 – Dec 2022· Results posted
Sponsor: NRG Oncology

Endometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated CarcinomaEndometrial Endometrioid Adenocarcinoma+13 more

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