Active, not recruitingInterventional · Not applicableNCT04226547 ↗Clinical Trial of Atrial Fibrillation Patients Comparing Left Atrial Appendage Occlusion Therapy to Non-vitamin K Antagonist Oral Anticoagulants
Active, not recruitingInterventional · Not applicableNCT04489823 ↗PARADIGM PARAvalvular Leak Closure With the Amplatzer Valvular Plug occluDer for Interventional Transcatheter Closure for PVL With Surgical bioloGical and Mechanical Heart ValveGeoffrey W BergmanPIInterventionDevice: AVP IIIDatesDec 2020 – Nov 2025SponsorAbbott Cardiovascular Systems, Inc.Paravalvular Aortic Regurgitation
Active, not recruitingInterventional · Not applicableNCT04722250 ↗SMall Annuli Randomized To Evolut™ or SAPIEN™ TrialGeoffrey W BergmanPIInterventionDevice: Medtronic Evolut PRO, Evolut PRO+ or Evolut FX (where commercially available) TAV Systems · Device: Edwards SAPIEN 3 or SAPIEN 3 Ultra THV SystemsDatesApr 2021 – Nov 2023· Results postedSponsorMedtronic, Inc.Symptomatic Aortic StenosisAortic Valve StenosisAortic Valve Replacement
Active, not recruitingInterventional · Not applicableNCT05893498 ↗Advancing Cath Lab Results With FFRangio Coronary Physiology AssessmentYuhei KobayashiPIGeoffrey W BergmanPIInterventionDevice: FFRangio · Device: FFR or NHPRDatesJun 2023 – May 2026 (est.)SponsorCathWorks, Inc.Percutaneous Coronary Intervention
TerminatedInterventional · Not applicableNCT03618095 ↗REPRISE IV: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of LOTUS Edge Valve System in IntermediatE Surgical Risk SubjectsGeoffrey W BergmanPIInterventionDevice: LOTUS Edge Valve SystemDatesJan 2019 – Mar 2021· Results postedSponsorBoston Scientific CorporationAortic Valve Stenosis
CompletedObservationalNCT04175626 ↗BIOTRONIK - A Prospective Multicenter Study to Confirm the SaFety and Effectiveness of the Orsiro SiroLimus Eluting Coronary Stent System in the Treatment Of Subjects With up to Three De Novo or Restenotic Coronary Artery Lesions - VIIGeoffrey W BergmanPIInterventionDevice: Orsiro DESDatesJan 2020 – Jan 2022· Results postedSponsorBIOTRONIK GmbH & Co.Coronary Artery DiseaseAtherosclerosis, CoronaryMyocardial Ischemia+3 more