Active, not recruitingInterventional · Not applicableNCT04226547 ↗Clinical Trial of Atrial Fibrillation Patients Comparing Left Atrial Appendage Occlusion Therapy to Non-vitamin K Antagonist Oral Anticoagulants
RecruitingInterventional · Not applicableNCT04339699 ↗STITCH - Prospective Multi Center Comparative Parallel Concurrent Study of the NobleStitch EL Compared to FDA Approved Amplatzer Occluder Device for Closure of Patent Foramen Ovale to Prevent Recurrent Ischemic StrokeHarsimran SinghPIInterventionDevice: NobleStitch™EL Suture Mediated Closure System · Device: Amplatzer PFO OccluderDatesJan 2021 – Dec 2026 (est.)SponsorNobles Medical Technologies II, Inc.Foramen Ovale, PatentStroke, Ischemic
Active, not recruitingInterventional · Not applicableNCT04818645 ↗Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients (ASSERT-AF)Gioia TurittoPIInterventionDevice: ASSERT Insertable Cardiac Monitor · Other: Conventional Management and monitoringDatesJan 2023 – Jul 2028 (est.)SponsorUniversity of RochesterAtrial FibrillationHeart Failure
RecruitingInterventional · Phase 2NCT05507138 ↗Efficacy and Target Engagement of a Digital Intervention to Improve Depression and Executive Dysfunction After StrokeAbhishek JaywantPIInterventionDevice: AKL-T01 · Behavioral: Metacognitive Strategy TrainingDatesMar 2023 – Jun 2027 (est.)SponsorWeill Medical College of Cornell UniversityExecutive DysfunctionDepressionStroke
RecruitingInterventional · Not applicableNCT05723926 ↗Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral AnticoagulationHooman KamelPIInterventionDevice: Vine FilterDatesJan 2026 – Dec 2028 (est.)SponsorJavelin Medical Ltd.Atrial FibrillationOral AnticoagulationStroke+1 more
RecruitingInterventional · Not applicableNCT06689878 ↗Mobile Cognitive Behavioral Therapy for StrokeAbhishek JaywantPIInterventionDevice: Mobile CBT for StrokeDatesFeb 2025 – Mar 2028 (est.)SponsorWeill Medical College of Cornell UniversityAnxietyStrokeDepression
RecruitingInterventional · Not applicableNCT07447934 ↗Vibrotactile Stimulation for Lower Limb SpasticityJoan StillingPIInterventionDevice: Vibrotactile Stimulation (Static Use) · Device: Vibrotactile Stimulation (Dynamic Use) · Device: Vibrotactile Stimulation (Neurophysiological Mechanism)DatesApr 2026 – Jun 2027 (est.)SponsorWeill Medical College of Cornell UniversityLower Limb Spasticity
RecruitingInterventional · Not applicableNCT07639606 ↗Mobile Cognitive Behavioral Therapy in Early Stroke RecoveryAbhishek JaywantPIInterventionDevice: Mobile Cognitive Behavioral Therapy AppDatesNov 2026 – Mar 2029 (est.)SponsorWeill Medical College of Cornell UniversityAnxietyStrokeDepression - Major Depressive Disorder