RecruitingInterventional · Not applicableNCT05190978 ↗Randomized Feasibility Trial for Mesh in Pre-Pectoral ReconstructionDavid M. OtterburnPIInterventionDevice: Acellular Dermal Matrix · Procedure: Reconstruction without ADMDatesOct 2022 – Apr 2027 (est.)
RecruitingInterventional · Not applicableNCT07110636 ↗A Prospective Randomized Basket Trial Evaluating the Clinical Utility of Plasma-based Microbial Cell-free Metagenomic Sequencing for Diagnosis and Management of Suspected Infections in Adult Immunocompromised OutpatientsAlexander DrelickPIInterventionDiagnostic test: Metagenomic plasma-based test for agnostic pathogen detectionDatesOct 2025 – Sep 2028 (est.)SponsorKarius, IncInfectionInfections, BacterialInfections, Fungal+2 more
CompletedObservationalNCT03924934 ↗Community-associated Highly-Resistant EnterobacteralesRosy Priya L KodiyanplakkalPIDatesMay 2019 – Dec 2024SponsorUniversity of North CarolinaEnterobacteriaceae InfectionsCommunity-Acquired InfectionsHealthcare Associated Infection+1 more
CompletedExpanded accessNCT04334070 ↗Novartis Multiple Patient Program for Lamprene® (Clofazimine) for the Treatment of Non-Tuberculous Mycobacterial (NTM) InfectionsOle VielemeyerPIInterventionDrug: Lamprene®/ClofazimineDatesStarted Mar 2024SponsorNovartis Pharmaceuticals CorporationNon-Tuberculous Mycobacterial (NTM) Infections
CompletedInterventional · Not applicableNCT04815876 ↗Randomized Trial Comparing Transperineal vs. Transrectal MRI-targeted Prostate Biopsy; Randomized Controlled Trial Assessing Transperineal Prostate Biopsy to Reduce Infection ComplicationsJim C. HuPIInterventionProcedure: Transperineal MRI-guided prostate biopsy · Procedure: Transrectal MRI-guided prostate biopsy · Drug: Antibiotic (prophylaxis)DatesJun 2021 – Oct 2025· Results postedSponsorWeill Medical College of Cornell UniversityInfection
CompletedInterventional · Not applicableNCT04843566 ↗Evaluation of Transperineal Biopsy Under Local Anesthesia, a Novel Approach to Decrease Post-Biopsy Infections and Improve Cancer DetectionJim C. HuPIInterventionProcedure: Transperineal MRI-guided prostate biopsy · Procedure: Transrectal MRI-guided prostate biopsy · Drug: Antibiotic (prophylaxis)DatesMar 2021 – Apr 2024· Results postedSponsorWeill Medical College of Cornell UniversityInfection