RecruitingInterventional · Phase 4NCT04262206 ↗PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE)
RecruitingInterventional · Not applicableNCT05081596 ↗PATH-Pain: A Primary Care-Based Psychosocial Intervention To Improve Cognitive and Depression Outcomes in Older Adults With MCI and Early Stage ADDimitris N KiossesPIInterventionBehavioral: PATH-PainDatesJun 2022 – Jul 2027 (est.)SponsorWeill Medical College of Cornell UniversityDepressionPainCognitive Impairment
RecruitingInterventional · Not applicableNCT06168604 ↗The Pain Identification and Communication Toolkit: A Training Program to Support Family Caregivers of Persons With ADRDCatherine RiffinPIInterventionBehavioral: Pain Identification and Communication Toolkit · Behavioral: Health Promotion ProgramDatesDec 2023 – Oct 2027 (est.)SponsorWeill Medical College of Cornell UniversityCaregiver BurdenCognitive ImpairmentDementia+2 more
RecruitingObservationalNCT06170268 ↗Alzheimer's National Registry for Treatment and DiagnosticsMiran W SalgadoPISonja BlumPIInterventionOther: Routine Care DocumentationDatesOct 2022 – Dec 2032 (est.)SponsorAlzheimer's Association National OfficeAlzheimer Disease
RecruitingInterventional · Phase 2NCT06502964 ↗Double-Blind, Placebo-Controlled Study of ALTO-101 in Patients With Schizophrenia and Cognitive ImpairmentAnthony O. AhmedPIInterventionDrug: ALTO-101 · Device: ALTO-101 Transdermal Delivery System · Drug: Placebo · Device: Placebo Transdermal Delivery SystemDatesJun 2024 – Feb 2026 (est.)SponsorAlto NeuroscienceSchizophreniaCognitive Impairment
RecruitingInterventional · Phase 2NCT07553338 ↗Safety Assessment of Leronlimab and Its Effect on Neuroinflammation Targets in Alzheimer's DiseaseTracy A. ButlerPIInterventionDrug: Leronlimab (700mg)DatesApr 2026 – Nov 2027 (est.)SponsorWeill Medical College of Cornell UniversityMild Cognitive Impairment (MCI) Due to Alzheimer's DiseaseAlzheimer's Disease