Scholars requires JavaScript. Please enable it in your browser to view this page.
Skip to main content
Scholars
Beta
Weill Cornell Medicine
Browse
About
Sign in
Loading co-authored publications…
Feedback
Scholars
/
Lukas Edward Dow, PhD
/
Co-authored with Teng Han
Co-authored publications
Lukas Edward Dow, PhD and Teng Han · 8 publications
CSV
Word
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.
Nature
· 2020
LE
Lukas Edward Dow
TH
Teng Han
DT
Duc-Huy Tran Nguyen
RS
Ryan Schreiner
+13 more →
SR
Shahin Rafii
PMID:
32908310
·
PMCID:
PMC7480005
·
DOI
·
234 citations
·
Abstract
An
In Vivo Kras
Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants.
Cancer discovery
· 2020
LE
Lukas Edward Dow
TH
Teng Han
MP
Maria Paz Zafra
MJ
Marie J Parsons
JK
Jangkyung Kim
+3 more →
PMID:
32792368
·
PMCID:
PMC7642097
·
DOI
·
110 citations
·
Abstract
Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy.
Cancer discovery
· 2020
LE
Lukas Edward Dow
TH
Teng Han
EM
Emma M Schatoff
PMID:
32703769
·
PMCID:
PMC7642035
·
DOI
·
58 citations
·
Abstract
Lineage Reversion Drives WNT Independence in Intestinal Cancer.
Cancer discovery
· 2020
LE
Lukas Edward Dow
TH
Teng Han
FT
Fanying Tang
MP
Maria Paz Zafra
CM
Charles Murphy
+4 more →
PMID:
32546576
·
PMCID:
PMC7541594
·
DOI
·
64 citations
·
Abstract
Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis.
Cancer discovery
· 2020
LE
Lukas Edward Dow
TH
Teng Han
ZC
Zhen Cao
CL
Charles L. Sawyers
SW
Scott W Lowe
PMID:
32376773
·
PMCID:
PMC7334089
·
DOI
·
45 citations
·
Abstract
Optimized base editors enable efficient editing in cells, organoids and mice.
Nature biotechnology
· 2018
LE
Lukas Edward Dow
TH
Teng Han
MP
Maria Paz Zafra
EM
Emma M Schatoff
AK
Alyna Katti
+3 more →
PMID:
29969439
·
PMCID:
PMC6130889
·
DOI
·
303 citations
·
Abstract
R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.
Nature communications
· 2017
LE
Lukas Edward Dow
TH
Teng Han
EM
Emma M Schatoff
CM
Charles Murphy
MP
Maria Paz Zafra
+1 more →
PMID:
28695896
·
PMCID:
PMC5508203
·
DOI
·
100 citations
·
Abstract
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer.
Nature biotechnology
· 2017
LE
Lukas Edward Dow
TH
Teng Han
KP
Kevin P O'Rourke
EL
Evangelia Loizou
+3 more →
SW
Scott W Lowe
PMID:
28459450
·
PMCID:
PMC5462850
·
DOI
·
217 citations
·
Abstract