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Lukas Edward Dow, PhD
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Co-authored with Bianca Diaz
Co-authored publications
Lukas Edward Dow, PhD and Bianca Diaz · 7 publications
CSV
Word
Genetic mechanisms of resistance to targeted KRAS inhibition.
bioRxiv : the preprint server for biology
· 2025
LE
Lukas Edward Dow
BJ
Bianca J Diaz
MK
Max Kops
SB
Sara Bernardo
AV
Adrian Vega-Perez
PMID:
40799582
·
PMCID:
PMC12340830
·
DOI
·
Abstract
Generation of precision preclinical cancer models using regulated in vivo base editing.
Nature biotechnology
· 2023
LE
Lukas Edward Dow
BJ
Bianca J Diaz
JZ
Jill Zimmerman
EE
Eric E Gardner
SW
Scott W Lowe
PMID:
37563300
·
PMCID:
PMC11295146
·
DOI
·
29 citations
·
Abstract
CRISPR in cancer biology and therapy.
Nature reviews. Cancer
· 2022
LE
Lukas Edward Dow
BJ
Bianca J Diaz
AK
Alyna Katti
PMID:
35194172
·
DOI
·
389 citations
·
Abstract
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Nature biotechnology
· 2022
LE
Lukas Edward Dow
BJ
Bianca J Diaz
ER
Edward R Kastenhuber
AK
Alyna Katti
KC
Kevan Chu
+2 more →
PMID:
35165384
·
PMCID:
PMC9232935
·
DOI
·
91 citations
·
Abstract
GO: a functional reporter system to identify and enrich base editing activity.
Nucleic acids research
· 2020
LE
Lukas Edward Dow
BD
Bianca Diaz
AK
Alyna Katti
JZ
Jill Zimmerman
MP
Maria Paz Zafra
PMID:
32112097
·
PMCID:
PMC7102966
·
DOI
·
29 citations
·
Abstract
Tankyrase inhibition sensitizes cells to CDK4 blockade.
PloS one
· 2019
LE
Lukas Edward Dow
BJ
Bianca J Diaz
EM
Emma M Schatoff
JZ
Jill Zimmerman
PMID:
31891587
·
PMCID:
PMC6938305
·
DOI
·
8 citations
·
Abstract
Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition.
Cancer discovery
· 2019
LE
Lukas Edward Dow
BJ
Bianca J Diaz
EM
Emma M Schatoff
MP
Maria Paz Zafra
AK
Alyna Katti
PMID:
31337618
·
PMCID:
PMC6774804
·
DOI
·
72 citations
·
Abstract