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Lukas Edward Dow, PhD
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Co-authored with Alyna Katti
Co-authored publications
Lukas Edward Dow, PhD and Alyna Katti · 8 publications
CSV
Word
CRISPR in cancer biology and therapy.
Nature reviews. Cancer
· 2022
LE
Lukas Edward Dow
AK
Alyna Katti
BJ
Bianca J Diaz
PMID:
35194172
·
DOI
·
389 citations
·
Abstract
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Nature biotechnology
· 2022
LE
Lukas Edward Dow
AK
Alyna Katti
BJ
Bianca J Diaz
ER
Edward R Kastenhuber
KC
Kevan Chu
+2 more →
PMID:
35165384
·
PMCID:
PMC9232935
·
DOI
·
91 citations
·
Abstract
Dietary fructose improves intestinal cell survival and nutrient absorption.
Nature
· 2021
LE
Lukas Edward Dow
AK
Alyna Katti
SR
Samuel R Taylor
SR
Shakti Ramsamooj
+6 more →
MD
Marcus D Goncalves
PMID:
34408323
·
PMCID:
PMC8686685
·
DOI
·
268 citations
·
Abstract
An
In Vivo Kras
Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants.
Cancer discovery
· 2020
LE
Lukas Edward Dow
AK
Alyna Katti
MP
Maria Paz Zafra
MJ
Marie J Parsons
JK
Jangkyung Kim
+3 more →
PMID:
32792368
·
PMCID:
PMC7642097
·
DOI
·
110 citations
·
Abstract
Base editing goes into hyperdrive.
Nature cell biology
· 2020
LE
Lukas Edward Dow
AK
Alyna Katti
PMID:
32393885
·
DOI
·
1 citations
GO: a functional reporter system to identify and enrich base editing activity.
Nucleic acids research
· 2020
LE
Lukas Edward Dow
AK
Alyna Katti
JZ
Jill Zimmerman
BD
Bianca Diaz
MP
Maria Paz Zafra
PMID:
32112097
·
PMCID:
PMC7102966
·
DOI
·
29 citations
·
Abstract
Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition.
Cancer discovery
· 2019
LE
Lukas Edward Dow
AK
Alyna Katti
EM
Emma M Schatoff
MP
Maria Paz Zafra
BJ
Bianca J Diaz
PMID:
31337618
·
PMCID:
PMC6774804
·
DOI
·
72 citations
·
Abstract
Optimized base editors enable efficient editing in cells, organoids and mice.
Nature biotechnology
· 2018
LE
Lukas Edward Dow
AK
Alyna Katti
MP
Maria Paz Zafra
EM
Emma M Schatoff
TH
Teng Han
+3 more →
PMID:
29969439
·
PMCID:
PMC6130889
·
DOI
·
303 citations
·
Abstract