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John Blenis, PhD
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Co-authored with Vi Vien Low
Co-authored publications
John Blenis, PhD and Vi Vien Low · 9 publications
CSV
Word
Isoleucine and valine promote prostate cancer progression via propionyl-CoA-mediated cholesterol metabolism.
Nature metabolism
· 2026
JB
John Blenis
VL
Vivien Low
ZL
Zhongchi Li
WJ
Wenbing Jin
LX
Leyi Xiao
+12 more →
PMID:
42625032
·
PMCID:
PMC13493318
·
DOI
·
Abstract
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment.
Science signaling
· 2022
JB
John Blenis
VL
Vivien Low
ZL
Zhongchi Li
PMID:
36346837
·
DOI
·
38 citations
·
Abstract
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.
Nature communications
· 2022
JB
John Blenis
VL
Vivien Low
ZL
Zhongchi Li
EE
Ethan Earlie
BP
Bobak Parang
+10 more →
PMID:
36266345
·
PMCID:
PMC9584945
·
DOI
·
72 citations
·
Abstract
Altered propionate metabolism contributes to tumour progression and aggressiveness.
Nature metabolism
· 2022
JB
John Blenis
VL
Vivien Low
TS
Tanya Schild
MN
Michal Nagiec
BE
Bethany E Schaffer
+1 more →
PMID:
35361954
·
PMCID:
PMC9050834
·
DOI
·
89 citations
·
Abstract
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma.
Cell reports
· 2021
JB
John Blenis
VL
Vivien Low
TS
Tanya Schild
CS
Christie Shea
BE
Bethany E Schaffer
+2 more →
PMID:
34133937
·
PMCID:
PMC12076440
·
DOI
·
37 citations
·
Abstract
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Nature
· 2020
JB
John Blenis
VL
Vivien Low
JE
Jennifer Endress
AR
Adam Rosenzweig
TS
Tanya Schild
+3 more →
PMID:
32814897
·
PMCID:
PMC7785256
·
DOI
·
216 citations
·
Abstract
Targeting the premetastatic niche: epigenetic therapies in the spotlight.
Signal transduction and targeted therapy
· 2020
JB
John Blenis
VL
Vivien Low
AP
Ana P Gomes
PMID:
32390001
·
PMCID:
PMC7211564
·
DOI
·
13 citations
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization.
Cancer cell
· 2019
JB
John Blenis
VL
Vivien Low
DI
Didem Ilter
AR
Adam Rosenzweig
ZS
Zih-Jie Shen
+10 more →
PMID:
31564638
·
PMCID:
PMC6801101
·
DOI
·
83 citations
·
Abstract
Unique Metabolic Adaptations Dictate Distal Organ-Specific Metastatic Colonization.
Cancer cell
· 2018
JB
John Blenis
VL
Vivien Low
TS
Tanya Schild
AP
Ana P Gomes
PMID:
29533780
·
PMCID:
PMC5889305
·
DOI
·
171 citations
·
Abstract