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Jochen Buck, MD, PhD
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Co-authored with Melanie Balbach
Co-authored publications
Jochen Buck, MD, PhD and Melanie Balbach · 12 publications
CSV
Word
Bovine serum albumin-induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation.
The Journal of physiology
· 2025
JB
Jochen Buck
MB
Melanie Balbach
LR
Lonny R. Levin
PMID:
40320899
·
PMCID:
PMC12856760
·
DOI
·
8 citations
·
Abstract
Cyclic AMP Rescue of Motility in Sperm Devoid of Soluble Adenylyl Cyclase.
International journal of molecular sciences
· 2025
JB
Jochen Buck
MB
Melanie Balbach
NR
Natalia Rivera-Sanchez
JF
Justine Fischoeder
+1 more →
CR
Carla Ritagliati
PMID:
40003956
·
PMCID:
PMC11855772
·
DOI
·
6 citations
·
Abstract
Capacitation induces changes in metabolic pathways supporting motility of epididymal and ejaculated sperm.
Frontiers in cell and developmental biology
· 2023
JB
Jochen Buck
MB
Melanie Balbach
LR
Lonny R. Levin
PMID:
37440924
·
PMCID:
PMC10335746
·
DOI
·
36 citations
·
Abstract
In vivo
characterization of sAC null sperm.
Frontiers in cell and developmental biology
· 2023
JB
Jochen Buck
MB
Melanie Balbach
CR
Carla Ritagliati
LR
Lonny R. Levin
PMID:
37152282
·
PMCID:
PMC10160483
·
DOI
·
12 citations
·
Abstract
On-demand male contraception via acute inhibition of soluble adenylyl cyclase.
Nature communications
· 2023
JB
Jochen Buck
MB
Melanie Balbach
TR
Thomas Rossetti
JF
Jacob Ferreira
+4 more →
LR
Lonny R. Levin
PMID:
36788210
·
PMCID:
PMC9929232
·
DOI
·
72 citations
·
Abstract
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.
Journal of medicinal chemistry
· 2022
JB
Jochen Buck
MB
Melanie Balbach
TR
Thomas Rossetti
JF
Jacob Ferreira
+2 more →
PT
Peter T Meinke
PMID:
36346696
·
PMCID:
PMC9866367
·
DOI
·
22 citations
·
Abstract
Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.
Molecular human reproduction
· 2021
JB
Jochen Buck
MB
Melanie Balbach
TR
Thomas Rossetti
CR
Carla Ritagliati
+2 more →
LR
Lonny R. Levin
PMID:
34463764
·
PMCID:
PMC8473925
·
DOI
·
52 citations
·
Abstract
Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).
ACS medicinal chemistry letters
· 2021
JB
Jochen Buck
MB
Melanie Balbach
JF
Jacob Ferreira
TR
Thomas Rossetti
+3 more →
PT
Peter T Meinke
PMID:
34413957
·
PMCID:
PMC8366019
·
DOI
·
22 citations
·
Abstract
Capacitation increases glucose consumption in murine sperm.
Molecular reproduction and development
· 2020
JB
Jochen Buck
MB
Melanie Balbach
LR
Lonny R. Levin
PMID:
32914502
·
PMCID:
PMC7730450
·
DOI
·
41 citations
·
Abstract
Metabolic changes in mouse sperm during capacitation†.
Biology of reproduction
· 2020
JB
Jochen Buck
MB
Melanie Balbach
LR
Lonny R. Levin
PMID:
32614044
·
PMCID:
PMC7822642
·
DOI
·
72 citations
·
Abstract
Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public-private drug discovery institute collaboration†.
Biology of reproduction
· 2020
JB
Jochen Buck
MB
Melanie Balbach
DH
David Huggins
PT
Peter T Meinke
LR
Lonny R. Levin
PMID:
32307523
·
PMCID:
PMC7401349
·
DOI
·
18 citations
·
Abstract
Using an Extracellular Flux Analyzer to Measure Changes in Glycolysis and Oxidative Phosphorylation during Mouse Sperm Capacitation.
Journal of visualized experiments : JoVE
· 2020
JB
Jochen Buck
MB
Melanie Balbach
LR
Lonny R. Levin
PMID:
32065141
·
DOI
·
16 citations
·
Abstract