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James C. Lo, PhD, MD
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Co-authored with Alfonso Rubio-Navarro
Co-authored publications
James C. Lo, PhD, MD and Alfonso Rubio-Navarro · 10 publications
CSV
Word
Secretory kinase FAM20C triggers adipocyte dysfunction, inciting insulin resistance and inflammation in obesity.
The Journal of clinical investigation
· 2025
JC
James C. Lo
AR
Alfonso Rubio-Navarro
AG
Ankit Gilani
BD
Benjamin D Stein
RL
Renan Lima
+4 more →
PMID:
41148235
·
PMCID:
PMC12721910
·
DOI
·
1 citations
·
Abstract
C3aR1 on β cells enhances β cell function and survival to maintain glucose homeostasis.
Molecular metabolism
· 2025
JC
James C. Lo
AR
Alfonso Rubio-Navarro
RL
Renan Lima
AL
Ang Li
AG
Ankit Gilani
+3 more →
PMID:
40189102
·
PMCID:
PMC12018202
·
DOI
·
6 citations
·
Abstract
Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease.
eLife
· 2025
JC
James C. Lo
AR
Alfonso Rubio-Navarro
EA
Edwin Alexander Homan
AG
Ankit Gilani
MA
Maya A Johnson
+2 more →
PMID:
39773465
·
PMCID:
PMC11709426
·
DOI
·
1 citations
·
Abstract
Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury.
Communications biology
· 2024
JC
James C. Lo
AR
Alfonso Rubio-Navarro
YX
Yu Xia
FD
Friederike Dündar
PZ
Paul Zumbo
+6 more →
PMID:
39627536
·
PMCID:
PMC11615278
·
DOI
·
11 citations
·
Abstract
Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome.
Nature communications
· 2024
JC
James C. Lo
AR
Alfonso Rubio-Navarro
MM
Maiko Matsui
AR
Aravind R Gade
+7 more →
GP
Geoffrey Pitt
PMID:
39420001
·
PMCID:
PMC11487186
·
DOI
·
5 citations
·
Abstract
Complement 3a Receptor 1 on Macrophages and Kupffer cells is not required for the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease.
medRxiv : the preprint server for health sciences
· 2024
JC
James C. Lo
AR
Alfonso Rubio-Navarro
EA
Edwin Alexander Homan
AG
Ankit Gilani
MA
Maya A Johnson
+3 more →
PMID:
38978661
·
PMCID:
PMC11230319
·
DOI
·
Abstract
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Cell metabolism
· 2021
JC
James C. Lo
AR
Alfonso Rubio-Navarro
MR
Moritz Reiterer
NG
Nicolas Gomez-Banoy
AG
Ankit Gilani
+10 more →
PMID:
34879241
·
PMCID:
PMC8650200
·
DOI
·
24 citations
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Cell metabolism
· 2021
JC
James C. Lo
AR
Alfonso Rubio-Navarro
MR
Moritz Reiterer
NG
Nicolas Gomez-Banoy
AG
Ankit Gilani
+10 more →
PMID:
34599884
·
PMCID:
PMC8443335
·
DOI
·
185 citations
·
Abstract
Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance.
medRxiv : the preprint server for health sciences
· 2021
JC
James C. Lo
AR
Alfonso Rubio-Navarro
MR
Moritz Reiterer
NG
Nicolas Gomez-Banoy
AG
Ankit Gilani
+7 more →
PMID:
33791724
·
PMCID:
PMC8010756
·
DOI
·
Abstract
Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans.
Nature medicine
· 2019
JC
James C. Lo
AR
Alfonso Rubio-Navarro
NG
Nicolas Gomez-Banoy
GL
Ge Li
MA
Maria A Pabón
+4 more →
PMID:
31700183
·
PMCID:
PMC7256970
·
DOI
·
153 citations
·
Abstract