Co-authored publications

Hagen Tilgner, PhD and Careen Foord · 10 publications

CSV Word

Spatial isoform sequencing at single-cell resolution reveals cell-type-specific spatial isoform variability in multiple brain cell types.
Nature methods · 2026
HTHagen TilgnerCFCareen FoordLMLieke Michielsen YMYelizaveta Mochalova TKTaewoo Kim+5 more →
PMID: 42697995PMCID: PMC13545012DOI
A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.
Cell reports · 2025
HTHagen TilgnerCFCareen FoordNBNatan BelchikovWHWen HuLFLi Fan+8 more →
PMID: 40913764PMCID: PMC12558363DOI5 citations
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.
Nature communications · 2025
HTHagen TilgnerCFCareen FoordWHWen HuLMLieke MichielsenBEBrian Evans+6 more →
PMID: 40883294PMCID: PMC12397408DOI16 citations
Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.
Nature biotechnology · 2025
HTHagen TilgnerCFCareen FoordWHWen HuJHJustine HsuLFLi Fan+9 more →
PMID: 40696189PMCID: PMC12425497DOI10 citations
Spatial isoform sequencing at sub-micrometer single-cell resolution reveals novel patterns of spatial isoform variability in brain cell types.
bioRxiv : the preprint server for biology · 2025
HTHagen TilgnerCFCareen FoordLMLieke MichielsenWHWen HuJJJulien Jarroux+2 more →
PMID: 40667010PMCID: PMC12262416DOI
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.
bioRxiv : the preprint server for biology · 2025
HTHagen TilgnerCFCareen FoordWHWen HuLMLieke MichielsenBEBrian Evans+6 more →
PMID: 40661641PMCID: PMC12259066DOI
ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's Disease.
bioRxiv : the preprint server for biology · 2024
HTHagen TilgnerCFCareen FoordWHWen HuJHJustine HsuLFLi Fan+9 more →
PMID: 38464236PMCID: PMC10925193DOI
From words to complete phrases: insight into single-cell isoforms using short and long reads.
Transcription · 2023
HTHagen TilgnerCFCareen FoordJJJulien Jarroux
PMID: 37314295PMCID: PMC10807471DOI10 citations
The variables on RNA molecules: concert or cacophony? Answers in long-read sequencing.
Nature methods · 2023
HTHagen TilgnerCFCareen FoordJHJustine HsuJJJulien JarrouxWHWen Hu+3 more →
PMID: 36635536DOI26 citations
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.
Nature biotechnology · 2022
HTHagen TilgnerCFCareen FoordSASimon A HardwickWHWen HuAJAnoushka Joglekar+8 more →
PMID: 35256815PMCID: PMC9287170DOI93 citations