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Frederick R. Maxfield, PhD
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Co-authored with Jonathan Ma
Co-authored publications
Frederick R. Maxfield, PhD and Jonathan Ma · 9 publications
CSV
Word
Real-time pH imaging of macrophage lysosomes using the pH-sensitive probe ApHID.
Cell reports methods
· 2025
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
SS
Santiago Sole Domenech
JD
J David Warren
PMID:
41138732
·
PMCID:
PMC12664887
·
DOI
·
1 citations
·
Abstract
Real-time pH imaging of macrophage lysosomes using the pH-sensitive probe ApHID.
Cell reports methods
· 2025
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
SS
Santiago Sole Domenech
JD
J David Warren
PMID:
41092905
·
PMCID:
PMC12570321
·
DOI
·
3 citations
·
Abstract
The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding.
The Journal of clinical investigation
· 2025
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
MM
Mattia Malvezzi
LT
Lala Tanmoy Das
+1 more →
GP
Geoffrey Pitt
PMID:
40794434
·
PMCID:
PMC12520690
·
DOI
·
3 citations
·
Abstract
High-Content Microscopy Drug Screening Platform for Regulators of the Extracellular Digestion of Lipoprotein Aggregates by Macrophages.
ACS pharmacology & translational science
· 2025
FR
Frederick R. Maxfield
CJ
Cheng-I Jonathan Ma
NS
Noah Steinfeld
PMID:
40567278
·
PMCID:
PMC12186755
·
DOI
·
1 citations
·
Abstract
Itraconazole and posaconazole, inhibitors of NPC1 sterol transport, act as pharmacological chaperones after washout.
The Journal of biological chemistry
· 2025
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
NS
Noah Steinfeld
PMID:
40516874
·
PMCID:
PMC12272866
·
DOI
·
1 citations
·
Abstract
The Na
V
1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding.
bioRxiv : the preprint server for biology
· 2025
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
LT
Lala Tanmoy Das
GP
Geoffrey Pitt
PMID:
40166257
·
PMCID:
PMC11957044
·
DOI
·
Abstract
A high-content microscopy drug screening platform for regulators of the extracellular digestion of lipoprotein aggregates by macrophages.
bioRxiv : the preprint server for biology
· 2024
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
NS
Noah Steinfeld
PMID:
39605493
·
PMCID:
PMC11601252
·
DOI
·
Abstract
Signaling pathways regulating the extracellular digestion of lipoprotein aggregates by macrophages.
Molecular biology of the cell
· 2023
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
NS
Noah Steinfeld
PMID:
37910189
·
PMCID:
PMC10881170
·
DOI
·
9 citations
·
Abstract
The formation and consequences of cholesterol-rich deposits in atherosclerotic lesions.
Frontiers in cardiovascular medicine
· 2023
FR
Frederick R. Maxfield
CJ
Cheng-I J Ma
NS
Noah Steinfeld
PMID:
36926046
·
PMCID:
PMC10011067
·
DOI
·
24 citations
·
Abstract