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Eftychia Apostolou, PhD
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Co-authored with Uk Jin Lee
Co-authored publications
Eftychia Apostolou, PhD and Uk Jin Lee · 8 publications
CSV
Word
Postmitotic transcription and 3D regulation show locus-specific and differentiation-specific sensitivity to cohesin depletion.
Nature genetics
· 2026
EA
Eftychia Apostolou
UJ
Uk Jin Lee
AL
Alejandra Laguillo-Diego
DM
Daniela Magliulo
WW
Wilfred Wong
+2 more →
PMID:
41974992
·
DOI
·
2 citations
·
Abstract
Disruption of TAD hierarchy promotes LTR co-option in cancer.
Nature genetics
· 2025
EA
Eftychia Apostolou
UJ
Uk Jin Lee
RY
Rui Yang
NA
Nawaf Alomran
AP
Alexander Polyzos
+6 more →
PMID:
40588507
·
PMCID:
PMC12283374
·
DOI
·
5 citations
·
Abstract
Three-dimensional regulatory hubs support oncogenic programs in glioblastoma.
Molecular cell
· 2025
EA
Eftychia Apostolou
UJ
Uk Jin Lee
SB
Sarah Breves
DC
Dafne Campigli Di Giammartino
SC
Stefano Cirigliano
+7 more →
PMID:
40147440
·
PMCID:
PMC12009607
·
DOI
·
8 citations
·
Abstract
Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion.
bioRxiv : the preprint server for biology
· 2025
EA
Eftychia Apostolou
UJ
Uk Jin Lee
AL
Alejandra Laguillo-Diego
WW
Wilfred Wong
BP
Bobbie Pelham-Webb
PMID:
40034648
·
PMCID:
PMC11875242
·
DOI
·
Abstract
Three-dimensional regulatory hubs support oncogenic programs in glioblastoma.
bioRxiv : the preprint server for biology
· 2024
EA
Eftychia Apostolou
UJ
Uk Jin Lee
SB
Sarah Breves
DC
Dafne Campigli Di Giammartino
SC
Stefano Cirigliano
+7 more →
PMID:
40034649
·
PMCID:
PMC11875237
·
DOI
·
Abstract
TAD hierarchy restricts poised LTR activation and loss of TAD hierarchy promotes LTR co-option in cancer.
bioRxiv : the preprint server for biology
· 2024
EA
Eftychia Apostolou
UJ
Uk Jin Lee
AP
Alexander Polyzos
SC
Shuyuan Cheng
+3 more →
PC
Ping Chi
PMID:
38895201
·
PMCID:
PMC11185511
·
DOI
·
Abstract
3D Enhancer-promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages.
Nature structural & molecular biology
· 2023
EA
Eftychia Apostolou
UJ
Uk Jin Lee
DM
Dylan Murphy
ES
Eralda Salataj
EC
Erin Char
+5 more →
PMID:
38053013
·
PMCID:
PMC10897904
·
DOI
·
36 citations
·
Abstract
Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression.
bioRxiv : the preprint server for biology
· 2023
EA
Eftychia Apostolou
UJ
Uk Jin Lee
DM
Dylan Murphy
ES
Eralda Salataj
EC
Erin Char
+5 more →
PMID:
37577543
·
PMCID:
PMC10422694
·
DOI
·
Abstract