Co-authored publications

Eftychia Apostolou, PhD and Dylan Murphy · 9 publications

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CRISPR Screening Uncovers a Long-Range Enhancer for ONECUT1 in Pancreatic Differentiation and Links a Diabetes Risk Variant.
bioRxiv : the preprint server for biology · 2024
EAEftychia ApostolouDMDylan MurphyWWWilfred WongQLQianzi Li+2 more →DHDanwei Huangfu
PMID: 38746154PMCID: PMC11092487DOI
3D Enhancer-promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages.
Nature structural & molecular biology · 2023
EAEftychia ApostolouDMDylan MurphyESEralda SalatajECErin CharCMChristopher M Uyehara+5 more →
PMID: 38053013PMCID: PMC10897904DOI36 citations
Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression.
bioRxiv : the preprint server for biology · 2023
EAEftychia ApostolouDMDylan MurphyESEralda SalatajECErin CharCMChristopher M Uyehara+5 more →
PMID: 37577543PMCID: PMC10422694DOI
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions.
Nature genetics · 2023
EAEftychia ApostolouDMDylan MurphyWWWilfred WongBPBess P RosenRARachel A Glenn+2 more →
PMID: 37488417PMCID: PMC11012226DOI38 citations
Discovery of Competent Chromatin Regions in Human Embryonic Stem Cells.
bioRxiv : the preprint server for biology · 2023
EAEftychia ApostolouDMDylan MurphyZTZakieh TayyebiWWWilfred Wong+2 more →DHDanwei Huangfu
PMID: 37398096PMCID: PMC10312725DOI
Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities.
bioRxiv : the preprint server for biology · 2023
EAEftychia ApostolouDMDylan MurphyMSManu SettyAPAlexander Polyzos+2 more →AHAnna-Katerina Hadjantonakis
PMID: 37034770PMCID: PMC10081288DOI
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions.
bioRxiv : the preprint server for biology · 2023
EAEftychia ApostolouDMDylan MurphyWWWilfred WongRGRachel GlennTVThomas Vierbuchen+1 more →
PMID: 36945628PMCID: PMC10028945DOI
Dynamic 3D Chromatin Reorganization during Establishment and Maintenance of Pluripotency.
Stem cell reports · 2020
EAEftychia ApostolouDMDylan MurphyBPBobbie Pelham-Webb
PMID: 33242398PMCID: PMC7724465DOI36 citations
KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks.
Nature cell biology · 2019
EAEftychia ApostolouDMDylan MurphyAPAlexander PolyzosAAAbderhman AbuhashemPCPaola Cavaliere+3 more →
PMID: 31548608PMCID: PMC7339746DOI157 citations