Scholars requires JavaScript. Please enable it in your browser to view this page.
Skip to main content
Scholars
Beta
Weill Cornell Medicine
Browse
About
Sign in
Loading co-authored publications…
Feedback
Scholars
/
David Eliezer, PhD
/
Co-authored with Igor Dikiy
Co-authored publications
David Eliezer, PhD and Igor Dikiy · 11 publications
CSV
Word
Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles.
The Journal of general physiology
· 2016
DE
David Eliezer
ID
Igor Dikiy
CN
Crina Nimigean
PMID:
27432996
·
PMCID:
PMC4969796
·
DOI
·
19 citations
·
Abstract
Semisynthetic and in Vitro Phosphorylation of Alpha-Synuclein at Y39 Promotes Functional Partly Helical Membrane-Bound States Resembling Those Induced by PD Mutations.
ACS chemical biology
· 2016
DE
David Eliezer
ID
Igor Dikiy
HA
Hilal A. Lashuel
PMID:
27356045
·
PMCID:
PMC5240779
·
DOI
·
70 citations
·
Abstract
STARD4 Membrane Interactions and Sterol Binding.
Biochemistry
· 2015
DE
David Eliezer
ID
Igor Dikiy
DB
David B Iaea
FR
Frederick R. Maxfield
PMID:
26168008
·
PMCID:
PMC4527246
·
DOI
·
52 citations
·
Abstract
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity.
The Journal of biological chemistry
· 2014
DE
David Eliezer
ID
Igor Dikiy
HA
Hilal A. Lashuel
PMID:
24936070
·
PMCID:
PMC4139205
·
DOI
·
169 citations
·
Abstract
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.
Human molecular genetics
· 2014
DE
David Eliezer
ID
Igor Dikiy
HA
Hilal A. Lashuel
PMID:
24728187
·
PMCID:
PMC4119404
·
DOI
·
216 citations
·
Abstract
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.
Human molecular genetics
· 2014
DE
David Eliezer
ID
Igor Dikiy
HA
Hilal A. Lashuel
PMID:
24412932
·
PMCID:
PMC4014189
·
DOI
·
201 citations
·
Abstract
N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes.
The Journal of biological chemistry
· 2013
DE
David Eliezer
ID
Igor Dikiy
PMID:
24338013
·
PMCID:
PMC3916564
·
DOI
·
169 citations
·
Abstract
¹H, ¹³C, and ¹⁵N backbone resonance assignments of the L124D mutant of StAR-related lipid transfer domain protein 4 (StARD4).
Biomolecular NMR assignments
· 2012
DE
David Eliezer
ID
Igor Dikiy
PMID:
22918595
·
PMCID:
PMC3594388
·
DOI
·
3 citations
·
Abstract
Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein.
The Journal of biological chemistry
· 2012
DE
David Eliezer
ID
Igor Dikiy
HA
Hilal A. Lashuel
PMID:
22718772
·
PMCID:
PMC3436566
·
DOI
·
152 citations
·
Abstract
Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125.
Journal of the American Chemical Society
· 2012
DE
David Eliezer
ID
Igor Dikiy
HA
Hilal A. Lashuel
PMID:
22339654
·
PMCID:
PMC3592575
·
DOI
·
96 citations
·
Abstract
Folding and misfolding of alpha-synuclein on membranes.
Biochimica et biophysica acta
· 2011
DE
David Eliezer
ID
Igor Dikiy
PMID:
21945884
·
PMCID:
PMC3288321
·
DOI
·
182 citations
·
Abstract