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David C Lyden, PhD, MD
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Co-authored with Michele Cioffi
Co-authored publications
David C Lyden, PhD, MD and Michele Cioffi · 6 publications
CSV
Word
Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2.
Cell
· 2025
DC
David C Lyden
MC
Michele Cioffi
SL
Serena Lucotti
CM
Candia M Kenific
JB
Jacob Benjamin Geri
+13 more →
PMID:
39938515
·
PMCID:
PMC12452024
·
DOI
·
59 citations
·
Abstract
Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression.
Nature cancer
· 2024
DC
David C Lyden
MC
Michele Cioffi
IW
Inbal Wortzel
IA
Ife Akano
LS
Lee Shaashua Berger
+7 more →
PMID:
39627554
·
PMCID:
PMC12185067
·
DOI
·
36 citations
·
Abstract
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Nature medicine
· 2024
DC
David C Lyden
MC
Michele Cioffi
LB
Linda Bojmar
LS
Lee Shaashua Berger
JK
Junbum Kim
+23 more →
PMID:
38942992
·
PMCID:
PMC11416063
·
DOI
·
64 citations
·
Abstract
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
iScience
· 2020
DC
David C Lyden
MC
Michele Cioffi
KG
Kirill Grigorev
CM
Cem Meydan
+10 more →
CE
Christopher E Mason
PMID:
33376973
·
PMCID:
PMC7756145
·
DOI
·
50 citations
·
Abstract
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell
· 2020
DC
David C Lyden
MC
Michele Cioffi
AH
Ayuko Hoshino
HS
Han Sang Kim
LB
Linda Bojmar
+33 more →
PMID:
32795414
·
PMCID:
PMC7522766
·
DOI
·
1,115 citations
·
Abstract
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Cell stem cell
· 2020
DC
David C Lyden
MC
Michele Cioffi
LY
Liuliu Yang
YH
Yuling Han
+17 more →
SC
Shuibing Chen
PMID:
32579880
·
PMCID:
PMC7303620
·
DOI
·
554 citations
·
Abstract