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David A. Scheinberg, MD, PhD
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Co-authored with Christopher Bourne
Co-authored publications
David A. Scheinberg, MD, PhD and Christopher Bourne · 11 publications
CSV
Word
Host Interactions with Engineered T-cell Micropharmacies.
Cancer immunology research
· 2023
DA
David A. Scheinberg
CM
Christopher M Bourne
PW
Patrick Wallisch
SP
Stephanie Pierre
KV
Kristen Vogt
+4 more →
PMID:
37379366
·
PMCID:
PMC10472090
·
DOI
·
4 citations
·
Abstract
Host-cell Interactions of Engineered T cell Micropharmacies.
bioRxiv : the preprint server for biology
· 2023
DA
David A. Scheinberg
CM
Christopher M Bourne
PW
Patrick Wallisch
SP
Stephanie Pierre
KV
Kristen Vogt
+4 more →
PMID:
37205431
·
PMCID:
PMC10187158
·
DOI
·
Abstract
Potentiating antibody-dependent killing of cancers with CAR T cells secreting CD47-SIRPα checkpoint blocker.
Blood
· 2023
DA
David A. Scheinberg
CM
Christopher M Bourne
KK
Keifer Kurtz
PW
Patrick Wallisch
SP
Stephanie Pierre
+2 more →
PMID:
36696633
·
PMCID:
PMC10163312
·
DOI
·
46 citations
·
Abstract
Unmasking the suppressed immunopeptidome of EZH2-mutated diffuse large B-cell lymphomas through combination drug treatment.
Blood advances
· 2022
DA
David A. Scheinberg
CM
Christopher M Bourne
ZE
Zita E H Aretz
ZM
Zaki Molvi
RS
Ron S Gejman
+1 more →
PMID:
35561310
·
PMCID:
PMC9327544
·
DOI
·
16 citations
·
Abstract
A TCR mimic CAR T cell specific for NDC80 is broadly reactive with solid tumors and hematologic malignancies.
Blood
· 2022
DA
David A. Scheinberg
CB
Christopher Bourne
ZE
Zita E H Aretz
ML
Michael Lau
MG
Michael G Kharas
PMID:
35427421
·
PMCID:
PMC9412008
·
DOI
·
18 citations
·
Abstract
Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma.
The Journal of clinical investigation
· 2022
DA
David A. Scheinberg
CM
Christopher M Bourne
AM
Ari M. Melnick
WB
Wendy Béguelin
PMID:
35380993
·
PMCID:
PMC9106353
·
DOI
·
23 citations
·
Abstract
Engineering CAR-T cells to activate small-molecule drugs in situ.
Nature chemical biology
· 2021
DA
David A. Scheinberg
CM
Christopher M Bourne
KK
Keifer Kurtz
BC
Broderick C Corless
AY
Aaron Y Chang
+2 more →
PMID:
34969970
·
PMCID:
PMC9152922
·
DOI
·
77 citations
·
Abstract
Incorporation of bacterial immunoevasins to protect cell therapies from host antibody-mediated immune rejection.
Molecular therapy : the journal of the American Society of Gene Therapy
· 2021
DA
David A. Scheinberg
CM
Christopher M Bourne
MM
Megan M Dacek
PMID:
34217891
·
PMCID:
PMC8636170
·
DOI
·
17 citations
·
Abstract
Low-dose CDK4/6 inhibitors induce presentation of pathway specific MHC ligands as potential targets for cancer immunotherapy.
Oncoimmunology
· 2021
DA
David A. Scheinberg
CM
Christopher M Bourne
ZE
Zita E H Aretz
PMID:
34104540
·
PMCID:
PMC8158036
·
DOI
·
22 citations
·
Abstract
Targeted Cellular Micropharmacies: Cells Engineered for Localized Drug Delivery.
Cancers
· 2020
DA
David A. Scheinberg
CM
Christopher M Bourne
MM
Megan M Dacek
KK
Keifer Kurtz
PC
Pedro C Silberman
+3 more →
PMID:
32764348
·
PMCID:
PMC7465970
·
DOI
·
26 citations
·
Abstract
ALK and RET Inhibitors Promote HLA Class I Antigen Presentation and Unmask New Antigens within the Tumor Immunopeptidome.
Cancer immunology research
· 2019
DA
David A. Scheinberg
CB
Christopher Bourne
CY
Claire Y Oh
MM
Megan M Dacek
EJ
Elliott J Brea
+1 more →
PMID:
31540894
·
PMCID:
PMC6891198
·
DOI
·
40 citations
·
Abstract