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Overview

An acclaimed physician-scientist with a focus on urologic oncology, Dr. Loda uses biochemical and genomic approaches to investigate the mechanisms by which prostate cancer hijacks cell metabolism to allow tumors to flourish.

Highlights

  1. 1
    Nature communications · 2024
    PMID: 38191471PMCID: PMC10774315DOISenior author34 citations
  2. 2
    Molecular cancer research : MCR · 2021
    PMID: 34880124PMCID: PMC9127877DOISenior author36 citations
  3. 3
    Science signaling · 2024
    PMID: 38593154PMCID: PMC11161871DOISenior author26 citations

Publications

528 publications

Active

6 grants
  • Sub-PI
    PRORUST: Exploiting lipid metabolic vulnerabilities to trigger prostate tumor cell death (Collab Agreement w/ J. Swinnen). Originating sponsor is Fonds voor Wetenschappelijk Onderzoek aka FWO.
    Fonds voor Wetenschappelijk Onderzoek Vlaanderen · 2025–2030 · via Katholieke Universiteit Leuven
    KUL 253649-01
  • Sub-PI
    HEROIC Prostate Cancer Precision Health (PCaPH) Africa1K: Powering Precision Health to Improve Prostate Cancer Outcomes in Africa
    U.S. Department of Defense · 2024–2028 · via University of Sydney
    HT9425-24-1-1116
  • PI
    Genomically-informed Morphological Stromal Signatures to Predict Lethal Prostate Cancer
    U.S. Department of Defense · 2025–2028
    HT9425-25-1-0385
  • MPI
    Investigating cell-intrinsic and extrinsic interactions in prostate cancer at the single cell level ("Core A: Pathobiology")
    National Cancer Institute · 2022–2027 · via Columbia University
    P01CA265768-05
  • Sub-PI
    Genomic Diversity of Prostate Cancer Across the African Diaspora
    National Cancer Institute · 2022–2027 · via Dana-Farber Cancer Institute
    R01CA259200-05
  • MPI
    The role of lipidomic and genetic alterations in the predictive response to AR selective inhibitor (ARSI) and in racial disparities in patients with metastatic castration-resistant prostate cancer (mCRPC).
    American Italian Cancer Foundation · 2025–2026
    AICF 241000-01
Completed grants (21)
  • Sub-PI
    High-risk prostate cancer in southern Africa, unravelling the genome and exposome (TARGET Africa)
    U.S. Department of Defense · 2022–2025 · via University of Sydney
    GIMR 213956-03
  • Sub-PI
    Neuronal function and incurable prostate cancer
    U.S. Department of Defense · 2022–2025 · via Cold Spring Harbor Laboratory
    W81XWH-22-1087-1
  • KP
    Colorectal Cancer (CRC) Cellular Heterogeneity, Metastasis, and a Spatially-resolved Molecular Atlas for Colon
    Gastro-Intestinal Research Foundation · 2022–2025
    GIRF 227268-01
  • KP
    Characterizing 3'-UTR biology as a mechanism of therapy response in high risk prostate cancer.
    U.S. Department of Defense · 2024–2025
    HT9425-24-1-0310
  • MPI
    Untangle The Role of Tumor Microenvironment in Prostate Cancer Initiation, Progression, and Metastatization With Single-Cell Analysis Technologies
    American Italian Cancer Foundation · 2024–2025
    AICF 231002-01
  • Co-I
    Decoding Bone Metastasis in Prostate Cancer: A Multimodal Approach Integrating Genomics and Imaging Data
    U.S. Department of Defense · 2024–2024
    HT94252410381
  • KP
    Loss of Stromal Androgen Receptor (AR) Signaling Contributes to Progression in Prostate Cancer
    American Italian Cancer Foundation · 2023–2024
    AICF 230990-01
  • KP
    Deciphering the role of androgen receptor in spatially resolved mesenchymal populations in prostate cancer
    Fondazione AIRC per la Ricerca sul Cancro · 2022–2024
    No publications yet
    FAIRC 215049-01
  • PI
    Targeting lipid metabolism and diet in patients with locally advanced prostate cancer
    Prostate Cancer Foundation · 2023–2023
    PCF 227920-01
  • PI
    Lipid elongation via ELOVL5: a novel target for advanced prostate cancer
    U.S. Department of Defense · 2019–2023
    W81XWH-19-1-0566
  • MPI
    Weill Cornell Medicine (WCM) SPORE in Prostate Cancer
    National Cancer Institute · 2017–2023
    P50CA211024-03
  • Sub-PI
    Cancer Epidemiology Cohort in Male Health Professionals
    National Cancer Institute · 2019–2022 · via Harvard School of Public Health
    U01CA167552-10
  • PI
    Pharmacologic Inhibition of Lipogenesis Suppresses AR and Its Splice Variants to Inhibit Progression of Castration-Resistant Prostate Cancer
    U.S. Department of Defense · 2019–2021
    W81XWH-17-1-0483
  • Sub-PI
    Precision Interception of Aggressive Prostate Cancer in African American Men
    National Cancer Institute · 2019–2021 · via Dana-Farber Cancer Institute
    P20CA233255-03
  • Sub-PI
    Targeting the p110beta isoform of P13 kinase in prostate cancer
    National Cancer Institute · 2019–2020 · via Dana-Farber Cancer Institute
    R01CA187918-05
  • PI
    Molecular Link Between Metabolic Syndrome and Prostate Cancer
    NCI · 2007–2019 · via NIH RePORTER
    R01CA131945-10
  • MPI
    Gleason-based mRNA and Metabolomic Profiling to Predict Prostate Cancer Progress
    NCI · 2002–2019 · via NIH RePORTER
    P50CA090381-15
  • PI
    Tissue and Pathology Core
    NCI · 2007–2019 · via NIH RePORTER
    P50CA127003-10
  • PI
    CA: Tissue and Pathology
    NCI · 2003–2015 · via NIH RePORTER
    P50CA090578-10
  • MPI
    Pathology Core
    NCI · 2002–2013 · via NIH RePORTER
    P01CA089021-10
  • MPI
    PALMITOYLATION SIGNATURE IN PROSTATE CANCER CELL LINES
    NCRR · 2010–2011 · via NIH RePORTER
    P41RR011823-15

Honors & distinctions

2 honors
  • Member · National Academy of Medicine · 2024
  • Member · Association of American Physicians

Clinical research

1 study

Active

1 study
  • PI
    Genomically Informed Morphological Stromal Signatures to Predict Lethal Prostate Cancer
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)

News mentions

Show 4 more mentions

Media highlights

1 clip

External relationships

Professional Services

San Raffaele Scientific Institute