Publications
14 publications
Funding
1 grant
Active
1 grant- MPIUM1AI104681-11ARLG Pneumonia Direct Pilot ("Study")National Institute of Allergy and Infectious Diseases · 2023–2026 · via Duke University
Clinical research
8 studies
Active
1 study- PINCT05421858An Interventional Efficacy and Safety Phase 3 Double-blind 2-arm Study to Investigate IV Followed by Oral Fosmanogepix Compared With IV Caspofungin Followed by Oral Fluconazole in Adult Participants With Candidemia and/or Invasive CandidiasisPHASE3 · Basilea Pharmaceutica, Ltd. · OPEN TO ACCRUAL (as of 2026)Candidemia; Candidiasis, Invasive
Completed & closed trials (7)
- PINCT05101187Phase III, Adjudicator-blinded, Randomised Study to Evaluate Efficacy and Safety of Treatment With Olorofim Versus Treatment With AmBisome® Followed by Standard of Care in Patients With Invasive Fungal Disease Caused by Aspergillus SpeciesPHASE3 · F2G Ltd · IRB STUDY CLOSURE (as of 2025)Invasive Aspergillosis
- PINCT06181669Pneumonia Direct PilotDuke University · IRB STUDY CLOSURE (as of 2025)Pneumonia, Bacterial; Ventilator Associated Pneumonia
- PILong-Term Follow-up of Study 32: an open-label single-arm Phase IIb study of F901318 as treatment of invasive fungal infections due to Lomentospora prolificans, Scedosporium spp., Aspergillus spp., and other resistant fungi in patients lacking suitable alternative treatment options (F901318/0032-LTFU)F2G Ltd · IRB STUDY CLOSURE (as of 2025)
- PINCT04673175A Pilot Study of Ceftolozane-Tazobactam in Conjunction With Rapid Molecular Diagnosis for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell TransplantationPHASE4 · Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2025)Pneumonia; Hematologic Malignancy; Pseudomonas Aeruginosa Infection; Bacteremia; Hematopoietic Stem Cell Transplant (HSCT)
- PINCT03583164Phase IIb Study of F901318 as Treatment of Invasive Fungal Infections Due to Lomentospora Prolificans, Scedosporium Spp., Aspergillus Spp., and Other Resistant Fungi in Patients Lacking Suitable Alternative Treatment OptionsPHASE2 · F2G Ltd · IRB STUDY CLOSURE (as of 2023)Invasive Fungal Infections
- PITreatment of a single patient infected with Mycobacterium haemophilum infection using Clofazimine (Lamprene)Novartis Pharmaceuticals Corporation · IRB STUDY CLOSURE (as of 2022)
- PICompassionate use of clofazimineWeill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2020)