Overview
Dr. Marco Seandel is an Associate Professor of Cell and Developmental Biology in Surgery at Weill Cornell Medical College. Dr. Seandel received his MD/PhD from the State University of New York at Stony Brook, completed his internal medicine residency at New York-Presbyterian/Weill Cornell Medical Center and his medical oncology fellowship at Memorial Sloan Kettering Cancer Center. His lab is keenly interested in the mechanisms by which monogenic and complex disorders become increasingly prevalent in children as a function of the father’s age at the time of conception. Projects in the laboratory relate to cancer risk, autism, and skeletal disorders among others. The lab uses adult spermatogonial stem cells in vitro, stem cell transplantation, human genomics, and mouse models to understand the origin and mechanisms of human disease.
Publications
36 publications
Funding
8 grantsView NIH portfolio on RePORTER ↗
Active
1 grant- MPIR01HD101452-03Negative feedback regulation of growth factor signaling in adult spermatogonial stem cellsEunice Kennedy Shriver National Institute of Child Health and Human Development · 2021–2026
Completed grants (7)
- MPIR21HD107212-01A1Methods for detection of dynamic intracellular signals in single adult spermatogonial stem cellsEunice Kennedy Shriver National Institute of Child Health and Human Development · 2023–2025
- PII9-A9-085The Paternal Germline as a Source of De Novo Cancer Risk in OffspringStarr Cancer Consortium · 2016–2019
- PI2016-007Generation and Functional Characterization of Primordial Germ Cells Derived From hESCsTri-Institutional Stem Cell Initiative (Weill Cornell) · 2016–2019
- PITRI-SCI WC 14030395-04Spermatogonial Stem Cells as a Source of De Novo Cancer Susceptibility MutationsTri-Institutional Stem Cell Initiative (Weill Cornell) · 2013–2019
- MPIP50HD076210-05Pathogenic disruption of small RNA function by de novo mutationsEunice Kennedy Shriver National Institute of Child Health and Human Development · 2017–2019 · via Cornell University - Ithaca
- PIDP2HD080352-03Stem Cell Competition as the Driver for Sporadic Human DiseasesEunice Kennedy Shriver National Institute of Child Health and Human Development · 2013–2018
- Co-IC029156A Shared Facility for the Derivation, Validation, and Distribution of Stem Cells for Disease ModelingNew York State Stem Cell Science (NYSTEM) · 2014–2018