Overview

1. 1
   Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.

   The Journal of biological chemistry · 2020

   RSRohit SharmaLALaura Alonso

   PMID: 32788214·PMCID: PMC7549035·DOI·Senior author·51 citations·Abstract
2. 2
   Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation.

   The Journal of clinical investigation · 2023

   HLHuguet Landa GalvanRSRohit SharmaDRDavid RedmondLALaura Alonso

   PMID: 37712417·PMCID: PMC10503800·DOI·Senior author·2 citations·Abstract
3. 3
   Preadmission predictors of severe COVID-19 in patients with diabetes mellitus.

   Journal of diabetes and its complications · 2021

   APAlpana P. ShuklaBTBeverly TchangFAFelicia Ann Mendelsohn CuranajJSJane Seley+2 more →LALaura Alonso

   PMID: 34099384·PMCID: PMC8162023·DOI·Senior author·6 citations·Abstract

• MPI

  GIP receptor signaling mechanisms

  National Institute of Diabetes and Digestive and Kidney Diseases · 2026–2031

  Abstract

  R01DK142926-01A1
• Co-I

  The Role of NAD+ Metabolism in Obesity-Induced Pancreatic Beta-Cell Dysfunction

  National Institute of Diabetes and Digestive and Kidney Diseases · 2025–2030

  Abstract

  R01DK143009-01
• Co-I

  Assessing the Impact of SARS-CoV-2 on Adipose Tissue Function and Glucose Homeostasis

  National Institute of Diabetes and Digestive and Kidney Diseases · 2023–2028

  Abstract

  R01DK132879-01A1
• PI

  Research Training in Endocrinology and Metabolism

  National Institute of Diabetes and Digestive and Kidney Diseases · 2023–2028Training

  Abstract & 1 publication

  T32DK131957-03
• PI

  Benefits and Harms of Activating ATF6 in Beta Cells

  National Institute of Diabetes and Digestive and Kidney Diseases · 2023–2026

  Abstract & 6 publications

  R01DK135304-04

• Member · American Society for Clinical Investigation · 2019

• Blocking a Cellular Stress Pathway May Help Preserve Insulin-Producing Cells

  October 20, 2026

  Researchers at Weill Cornell Medicine have identified a molecular pathway that contributes to the death of insulin-producing beta cells in the pancreas. Experiments with preclinical models and human pancreatic cells found that blocking certain proteins in the pathway helped protect beta cells from excessive cellular stress.

• Boosting Beta Cells to Treat Type 2 Diabetes

  November 8, 2023

  Researchers at Weill Cornell Medicine have uncovered a novel route to stimulate the growth of healthy insulin-producing pancreatic beta cells in a preclinical model of diabetes. The findings hold promise for future therapeutics that will improve the lives of individuals with type 2 diabetes—a condition that affects more than half a billion people worldwide.

• Dr. Laura Alonso Chosen for Fellowship in Prestigious Executive Leadership Program

  June 23, 2022

  Dr. Laura Alonso, chief of the Division of Endocrinology, Diabetes and Metabolism and the Herbert J. and Ann L. Siegel Distinguished Professor of Medicine at Weill Cornell Medicine, has been selected to be a fellow of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program at Drexel University College of Medicine.

• COVID-19 May Trigger Hyperglycemia and Worsen Disease by Harming Fat Cells

  October 1, 2021

  COVID-19 may bring high risks of severe disease and death in many patients by disrupting key metabolic signals and thereby triggering hyperglycemia, according to a new study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.

• Elegant Solution: Endocrinology Chief Dr. Laura Alonso—A Specialist in Diabetes Research and Treatment—is Exploring Ways to Restore the Body’s Insulin Production

  September 2, 2020

  Endocrinology Chief Dr. Laura Alonso—A specialist in diabetes research and treatment—is exploring ways to restore the body’s insulin production

• Blocking Stress Pathway Protects Insulin-Producing Cells In Mouse And Human-Cell Experiments

  FingerLakes1.com · October 22, 2026

• AR

  Andrew Rappa

  Pharmacology (PhD)

  2 co-pubs
  • JNK and p53 cause human and mouse β cell death during excessive unfolded protein response.
    The Journal of clinical investigation · 2026
  • NRH, a potent NAD⁺ enhancer, improves glucose homeostasis and lipid metabolism in diet-induced obese mice through an active adenosine kinase pathway.
    Metabolism: clinical and experimental · 2024

  View all 2 →
• LD

  Lorraine de Oliveira

  Postdoc mentee · 2021–2022
• RD

  Ricardo da Costa e Sousa

  Postdoc mentee · 2021–2022